When facing zone defense, Bethel University (MN) OC Colin Duling teaches the Quarterback to manipulate the conflict defender.  The responsibility to manipulate the non-conflict defender falls on the receivers.

In the video below, he describes a few scenarios, including a drill and how they practice the concept as a team.   Coach Duling uses game film to show how they apply it.

The video is a portion of his Glazier Drive presentation, WR Technique & Drills vs. Zone Coverage.

Coverage Identification Teaching Points

Identifying Man vs Zone

• Eyes
• Leverage

Objective

• vs Man Coverage = "Create space" to create a throwing window
• vs Zone Coverage = “Find space” to create a throwing window

Zone Coverage

• Identify "conflict defender" through our count system
• Quarterback: manipulate conflict defender's movements
  Shoulders, Eyes, Drop, Pump Fake, Etc
• Receiver: Manipulate Non-Conflict Defender's Movements
  Route Stem
  Creating Space By Expanding Zones
  Movement of Defender's Hips to Slow Down Break